June 2010 Archives

Joan Richtsmeier and Chris Klingenberg are chairing a symposium entitled "Genetic and developmental basis of the evolution of complex traits" at the third meeting of the European society for Evolutionary Developmental biology (EED) in Paris on July 9, 2010.
Joan Richtsmeier will be presenting a poster at the third meeting of the European society for Evolutionary Developmental biology (EED) in Paris from July 6-9, 2010.
Research Assistant Neus Martínez-Abadías will attend the third conference of the European Society for Evolutionary and Developmental Biology (EED) that will take place in Paris (France) from 6 to 9 July.  Neus will present a poster about the correspondence of developmentally determined craniofacial variation in humans and mice.  This work has been done in collaboration with researchers from the University of Calgary, University of Vienna, Stockholms Universitet and Universitat de Barcelona, under the supervision of Dr. Joan Richtsmeier and Dr. Benedikt Hallgrímsson.

Congratulations to graduate alumna Heather Norton (Ph.D. 2005) on her acceptance of a tenure-track assistant professor appointment at the University of Cincinnati Department of Anthropology, part of the McMicken College of Arts and Sciences Molecular Marker Initiative. She will be starting her new position in the fall.  Congratulations Heather!

Yann Heuzé1 along with coauthors Simeon A. Boyadjiev2, Jeffrey L. Marsh3, Alex A. Kane4, Elijah Cherkez2, James E. Boggan5 and Joan T. Richtsmeierrecently had a paper accepted for publication.  The title of the paper is "New insights into the relationship between suture closure and craniofacial dysmorphology in sagittal nonsyndromic craniosynostosis."  The paper will be the cover article of the August 2010 issue in the Journal of Anatomy.


1Department of Anthropology, The Pennsylvania State University, PA, USA.

2Section of Genetics, Department of Pediatrics, University of California Davis, Sacramento CA, USA.

3St. John's Mercy Children's Hospital, St Louis MO, USA

4Washington University School of Medicine, Saint Louis MO, USA

5Department of Neurological Surgery, University of California Davis, Sacramento CA, USA

 

Abstract

Premature closure of the sagittal suture occurs as an isolated (nonsyndromic) birth defect, or as a syndromic anomaly in combination with other congenital dysmorphologies. The genetic causes of sagittal nonsyndromic craniosynostosis (NSC) remain unknown. Though variation of the dysmorphic (scaphocephaly) skull shape of sagittal NSC cases has been acknowledged, this variation has not been quantitatively studied in 3D. We have analyzed the computed tomography skull images of 43 infants (aged from 0.9 to 9 months) with sagittal NSC using anatomical landmarks and semilandmarks to quantify and characterize the within-sample phenotypic variation. Suture closure patterns were defined by dividing the sagittal suture into three sections (anterior, central, posterior) and coding each section as "closed" or "fused". Principal components analysis of the Procrustes shape coordinates representing skull shape of 43 cases of NSC did not separate individuals by sex, chronological age, or dental stages of deciduous maxillary first molar. However, analysis of suture closure pattern allowed separation of these data. The central section of the sagittal suture appears to be the first to fuse. Then, at least two different developmental paths towards complete fusion of the sagittal suture exist; either the anterior section or the posterior section is the second to fuse. Results indicate that according to the sequence of sagittal suture closure patterns, different craniofacial complex shapes are observed. The relationship between craniofacial shape and suture closure indicates not only which suture fused prematurely (in our case the sagittal suture), but also the pattern in which the suture closes. Whether these patterns indicate differences in aetiology cannot be determined with our data and requires analysis of longitudinal data, most appropriately of animal models where prenatal conditions can be monitored.

Graduate student John Starbuck is currently attending the 15th Annual Summer Institute of Statistical Genetics at the University of Washington from June 14-23, 2010. John was fortunate enough to obtain funding from several sources to attend this event: Hill Fellowship Pre-Comprehensive Examination Award, Paul T. Baker Research Travel Fund in Human Biology and Anthropology Award, Research and Graduate Studies Office travel grant, Office of Graduate Educational Equity Program, and a Summer Institute of Statistical Genetics tuition scholarship for 3 modules and travel through the University of Washington.
Graduate student John Starbuck will attend the 38th Annual National Down Syndrome Congress  in Lake Buena Vista, FL from July 16-18, 2010.  Using the 3dMD photographic system, John will collect 3D facial images of individuals with Down syndrome and their siblings to expand his dissertation dataset.
Chris Percival will be attending the Georgetown Summer Medical Institute to take the Human Gross Anatomy course this summer.
Article information: Roseman, CC, KE Willmore, J Rogers, C Hildebolt, BE Sadler, JT Richtsmeier, JM Cheverud. 2010 Genetic and environmental contributions to variation in baboon cranial morphology, in press.

Look for cool baboon graphics from this project on the cover of the September issue of AJPA!

See http://www.hominid.psu.edu for additional information on this project.
Puts.jpgDavid Puts' paper "Beauty and the Beast: Mechanisms of Sexual Selection in Humans" appeared in the May issue of Evolution and Human Behavior. Follow this link to the article http://www.ehbonline.org/article/S1090-5138%2810%2900027-9/abstract

The Economist commented on the paper in their May 20 issue through their article "To Get the Girl - Fighting off Rivals May be Responsible for Masculine Traits". See link to this article
http://www.economist.com/science-technology/displaystory.cfm?story_id=16160490

Dr. Puts replies to the comments received by the publication in the May 24 issue of The Economist. See link below for his comments.
http://www.economist.com/user/David_Puts/comments

Penn State Live also reported on the paper in their May 13 issue. See link below
:

http://live.psu.edu/story/46732

Alumni Abby Bigham and Jason DeLeon (both 2008 Ph.D. graduates) have accepted tenure-track positions in the Department of Anthropology at the University of Michigan-Ann Arbor.  Jason will begin his position next year and Abby will begin after her post-doc is completed at the University of Washington.