Winograd Group Research Areas:
The long-term goal of this research is to establish the
chain of molecular events associated with neurotransmitter release at the
single cell and subcellular level.
This work describes a long term research program aimed toward understanding the fundamental aspects of the interaction of energetic particles with solids and toward developing novel applications using these beams in a variety of surface chemistry studies.
This is a new program aimed toward exploiting recent
developments in mass spectrometry imaging. With this tool, it will be possible
to determine the chemical composition of the near surface region of a variety
of materials with high molecular specificity and with nanometer scale lateral
Lipid MAPS Consortium (NIH)
The LIPID MAPS (Lipid Metabolites and Pathways Strategy) consortium is a multi-institutional effort to further our understanding of lipid metabolism and the role lipids play in diseases such as diabetes, stroke, and cancer. The consortium takes a systems biology approach using the mouse macrophage as a model system, and provides tools and resources for the wider community. See About the consortium for more information.
The mission of this National Resource is to advance the technology of Imaging Mass Spectrometry, to facilitate the application of this novel imaging modality to problems of biological and clinical significance, and to promote the adoption of these technologies by a larger community of scientists and clinicians. Technology development is conducted by an interdisciplinary team of scientists and engineers, both within the Resource and through collaborative relationships with other universities, research institutes, and private industry. Development milestones are guided by Driving Biological Projects that require specific advancements in Imaging Mass Spectrometry in order to address biological problems. By working together, we anticipate new insights into these biological systems and a better understanding of health and disease at the molecular level that translates to improved patient care.