Special Issue for Statistical Genomics in Clinical Trials was edited by Dr. Rongling Wu and Dr. Min Lin at Duke University in Journal of Biopharmaceutical Statistics, Volume 20.

Special Issue for Statistical Genomics in Clinical Trials has appeared in this journal, Volume 20, March - April 2010 (pages: 191-490). This special issue was edited by Dr. Rongling Wu and Dr. Min Lin at Duke University.

The following is the contents of this issue. For a detail, please click the journal's website.

The Contents

Special Issue of Statistical Genetics and Genomics in Clinical Trials: Guest Editor's Note
Rongling Wu ;Min Lin

Pages 191-192, Abstract
Section 1: Gene Expression Analysis
Discrete Nonparametric Algorithms for Outlier Detection with Genomic Data
Debashis Ghosh

Pages 193-208, Abstract
Network-Based Empirical Bayes Methods for Linear Models with Applications to Genomic Data
Caiyan Li ; Zhi Wei ;Hongzhe Li

Pages 209-222, Abstract
Optimized Ranking and Selection Methods for Feature Selection with Application in Microarray Experiments
Xinping Cui ; Haibing Zhao ;Jason Wilson

Pages 223-239, Abstract
Evaluation of a Statistical Equivalence Test Applied to Microarray Data
Jing Qiu ;Xiangqin Cui

Pages 240-266, Abstract
A Semiparametric Bayesian Approach for Estimating the Gene Expression Distribution
Fei Zou ; Hanwen Huang ;Joseph G. Ibrahim

Pages 267-280, Abstract
Weighted Gene Coexpression Network Analysis: State of the Art
Wei Zhao ; Peter Langfelder ; Tova Fuller ; Jun Dong ; Ai Li ;Steve Hovarth

Pages 281-300, Abstract
Section 2: Pharmacogenetics
Testing Gene?Treatment Interactions in Pharmacogenetic Studies
Min He ;Andrew Allen

Pages 301-314, Abstract
Genotype-Based Risk and Pharmacogenetic Sampling in Clinical Trials
Nicholas J. Schork ;Eric J. Topol

Pages 315-333, Abstract
Haplotype-Based Pharmacogenetic Analysis for Longitudinal Quantitative Traits in the Presence of Dropout
Jung-Ying Tzeng* ; Wenbin Lu* ; Mark W. Farmen ; Youfang Liu ;Patrick F. Sullivan

Pages 334-350, Abstract
Modeling the Genetic Etiology of Pharmacokinetic?Pharmacodynamic Links with the Arma Process
Min Lin ; Arthur Berg ;Rongling Wu

Pages 351-372, Abstract
Section 3: Systems Biology and Predictive Models
A Systems Biology Approach for Identifying Novel Pathway Regulators in eQTL Mapping
Shaoyu Li ; Qing Lu ;Yuehua Cui

Pages 373-400, Abstract
Bagging Optimal ROC Curve Method for Predictive Genetic Tests, with an Application for Rheumatoid Arthritis
Qing Lu ; Yuehua Cui ; Chengyin Ye ; Changshuai Wei ;Robert C. Elston

Pages 401-414, Abstract
Practical Issues in Building Risk-Predicting Models for Complex Diseases
Jia Kang ; Judy Cho ;Hongyu Zhao

Pages 415-440, Abstract
Section 4: Linkage Disequilibrium Analysis and QTL Mapping
Summarizing and Quantifying Multilocus Linkage Disequilibrium Patterns with Multi-Order Markov Chain Models
Sheng Feng ;Shengchu Wang

Pages 441-453, Abstract
Current Progress on Statistical Methods for Mapping Quantitative Trait Loci from Inbred Line Crosses
Luciano Da Costa E Silva ;Zhao-Bang Zeng

Pages 454-481, Abstract
Book Reviews
A Review of: "Robust Methods in Biostatistics, by S. Heritier, E. Cantoni, S. Copt, and M.-P. Victoria-Feser"
Chichester, UK: Wiley, 2009, ISBN 978-0-470-02726-4, xiv + 268 pp., $110.

Dirk F. Moore

Pages 482-484, Abstract
A Review of: "ROC Curves for Continuous Data, by W. J. Krzanowski and D. J. Hand"
Boca Raton, FL: Chapman & Hall/CRC, 2009, ISBN 978-1-4398-0021-8, xiv + 241 pp., $69.95.

Mithat Gonen

Pages 485-487, Abstract
A Review of: "Gene Expression Studies Using Affymetrix Microarrays, by H. Gohlmann and W. Talloen"
Boca Raton, FL: Chapman & Hall/CRC, 2009, ISBN 978-1-4200-6515-2, 327 pp., $89.95.

Monnie McGee

Pages 488-490, Abstract
Page 491,Abstract